DBCO-TEG (5')

Code : [DBCO-TEG]

Modification : DBCO-TEG (5')

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC

26-6928
Click Chemistry
[DBCO-TEG]
Y
N
N
570.57
-
PS26-6928.pdf
-
-
-

Catalog No	Scale	Price
26-6928-06	5 umol	$2,016.00

Related Modifications
DBCO PC NHS	DBCO PEG13 NHS	BCN Endo Internal
Azide C3 3'	DBCO-TEG (5')	DBCO-dT
BCN-3' (Bicyclononyne) 3'	Azide-C4 NHS (butyrate)	Azide-C2 NHS
BCN Endo 5' (Bicyclononyne) 5'	DBCO-C6 NHS	Azide C6 (5')
Azide dT (5')	DBCO-C2 NHS	DBCO PEG4 NHS

DBCO-TEG, DBCO-dT and DBCO Serinol are discontinued modifications due to their instability during direct oligo synthesis protocols. We offer a range of post synthesis DBCO NHS modifications as alternate. See above related modifications.

Click here for a complete list of Click Chemistry Oligo Modifications

Cyclooctyne-based (dibenzocyclooctynes, DBCO) modifications offers the ease of copper-free click reagents. These are simple to use and has excellent click performance in 17 hours or less at room temperature. Gene Link offers 5'-DBCO-TEG for preparing oligos with 5�-DBCO and a 15 tom triethylene glycol spacer arm, DBCO-dT for inserting a DBCO group at any position within the oligonucleotide and DBCO-sulfo-NHS Ester is also offered for post-synthesis conjugation reactions. DBCO-modified oligos may be conjugated with azides in organic solvents, such as DMSO, or aqeous buffers. Depending on the azide used, the reaction will go to completion in 4-17 hours at room temperature.

Glen Report 27.1: Technical Brief - DBCO-dT - An Unusual Case of Iodine Sensitivity

- DBCO-TEG (5')