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Modification : Convertible dU & dC
Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC
26-6608
Convertible Bases
[O4-Tri-dU]
Y
Y
Y
289.18
7.4
PS26-6608.pdf
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| Catalog No | Scale | Price |
| 26-6608-05 | 50 nmol | $333.00 |
| 26-6608-02 | 200 nmol | $333.00 |
| 26-6608-01 | 1 umol | $450.00 |
| 26-6608-03 | 2 umol | $525.00 |
| 26-6608-06 | 5 umol | $1,575.00 |
| 26-6608-10 | 10 umol | $2,799.00 |
| 26-6608-15 | 15 umol | $3,499.00 |
| Discounts are available for Convertible dU & dC! |
| Modification* Discount Price Structure |
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1 site/order
|
List price
|
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2 sites/order
|
10% discount
|
|
3 sites/order
|
20% discount
|
|
4 sites/order
|
30% discount
|
|
5-9 sites/order
|
50% discount
|
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10+ sites/order
|
60% discount
|
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*Exceptions apply
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Gene Link supplies Convertible modified oligos protected with oligo bound to CPG solid support or can conjugate the convertible site to user specified ligand.
Convertible dU & dC (O4 Triazolyl dU) monomer can be used to introduce a variety of modifications at the convertible position, including N, O and S modifications.
The triazolyl pyrimidine convertible nucleosides allow oligonucleotides to be produced containing: 4-thio derivatives for cross linking reactions; 4-amino derivatives for DNA structural research; O4-alkyl derivatives for carcinogenesis studies; and offer the potential for the introduction of 13C, 15N and 17O labels for NMR experiments.
See examples below of Convertible dU & dC (O4 Triazolyl dU) to various amino derivatives.
See this link for Glen Research Technical Report (pdf) for Convertible bases.
Convertible Bases.
See this link for Glen Research Technical Report for Convertible bases.
Convertible Bases.
References
1. A.M. MacMillan and G.L. Verdine, Tetrahedron, 1991, 14, 2603-2616.
2. Y.Z. Xu, Q. Zheng, and P.F. Swann, J. Org. Chem., 1992, 57, 3841.
- Convertible dU & dC (O4 Triazolyl dU)
Oligo Purification