dideoxy G 5' (2'3-ddG)

ddG-5'

Code : [ddG-5]

Modification : ddG-5'

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC

26-6338
End Blockers
[ddG-5]
Y
N
N
313.2
11.5
PS26-6338.pdf
-
-
-

Catalog No	Scale	Price
26-6338-05	50 nmol	$297.00
26-6338-02	200 nmol	$297.00
26-6338-01	1 umol	$445.00
26-6338-03	2 umol	$801.00
26-6338-06	5 umol	$2,002.50
26-6338-10	10 umol	$3,560.00
26-6338-15	15 umol	$4,450.00

Discounts are available for ddG-5'!
Modification* Discount Price Structure
1 site/order	List price
2 sites/order	10% discount
3 sites/order	20% discount
4 sites/order	30% discount
5-9 sites/order	50% discount
10+ sites/order	60% discount
*Exceptions apply

Related Modifications
ddC-5'	ddG-5'	ddA-5'
Inverted dG (reverse linkage)	ddT-5'	ddC-3'
Inverted dT (reverse linkage)

Dideoxyguanosine (ddG) is a dideoxyribonucleoside that can only be used to block the 5' end. Use ddC-3' or Spacer C3 to block the 3' end from polymerase extension. ddG is a synthetic analog of deoxyguanosine, in ddG, both the 2'- and 3' -positions of the ribose have a hydrogen (-H) group substituted for the -OH group, whereas in dG, only the 2'-position is so substituted. ddG is added to the 5'-end of an oligo via 5'-to-5' synthesis, using a 2',3'-ddG, 5'-phosphoramidite. Purification must be by PAGE purification, since such an oligo will not have a trityl group (necessary for RPC purification).

ddC-3' should be used as a 3'-end blocking moiety (see ddC technical sheet).

- dideoxy G 5' (2'3-ddG)