N-POM Caged-dT

Code : [N-POM-Cg-dT]

Modification : N-POM Caged-dT

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC

26-6563
Structural Studies
[N-POM-Cg-dT]
Y
Y
Y
527.38
8.4
PS26-6563.pdf
-
-
-

Catalog No	Scale	Price
26-6563-05	50 nmol	$485.00
26-6563-02	200 nmol	$485.00
26-6563-01	1 umol	$526.00
26-6563-03	2 umol	$748.00
26-6563-06	5 umol	$2,241.00
26-6563-10	10 umol	$3,987.00
26-6563-15	15 umol	$4,984.00

Discounts are available for N-POM Caged-dT!
Modification* Discount Price Structure
1 site/order	List price
2 sites/order	10% discount
3 sites/order	20% discount
4 sites/order	30% discount
5-9 sites/order	50% discount
10+ sites/order	60% discount
*Exceptions apply

Related Modifications
PC Spacer (photocleavable)	cnvK Photo Cross Linker	PC Biotin (photocleavable)
PC Amino C6 (Photocleavable)	PC Linker (photocleavable)

Photo Activation Modification

N-POM Caged-dT can be used in the synthesis of caged oligonucleotides whose function is restored after uncaging by UV light at a wavelength that causes no DNA damage. The NPOM-Caged-dT, where the nucleobase is caged with the photolabile group, 6-nitropiperonyloxymethyl (NPOM), which can be removed using UV light at 365nm. Oligonucleotides containing NPOM-Caged-dT every five or six bases do not hybridize to their complementary strand. Photo-uncaging of the caged oligonucleotide is then easily carried out with UV light at 365 nm for seconds to minutes to restore the activity of the oligonucleotide. - N-POM Caged-dT